SIS-015832 MW < 50.0 or > 500.0 SIS-015834 MW < 50.0 or > 500.0 SIS-016006 MW < 50.0 or > 500.0 SIS-019560 MW < 50.0 or > 500.0 SIS-019584 MW < 50.0 or > 500.0 SIS-019585 MW < 50.0 or > 500.0 SIS-019633 MW < 50.0 or > 500.0 SIS-019645 MW < 50.0 or > 500.0 SIS-019670 MW < 50.0 or > 500.0 SIS-019727 MW < 50.0 or > 500.0 SIS-019728 MW < 50.0 or > 500.0 SIS-019750 MW < 50.0 or > 500.0 SIS-019764 MW < 50.0 or > 500.0 SIS-019848 MW < 50.0 or > 500.0 SIS-019849 MW < 50.0 or > 500.0 SIS-020038 MW < 50.0 or > 500.0 SIS-020158 MW < 50.0 or > 500.0 SIS-020171 MW < 50.0 or > 500.0 SIS-020198 MW < 50.0 or > 500.0 SIS-020204 MW < 50.0 or > 500.0 SIS-020213 MW < 50.0 or > 500.0 SIS-020244 MW < 50.0 or > 500.0 SIS-020274 MW < 50.0 or > 500.0 SIS-020277 MW < 50.0 or > 500.0 SIS-020304 MW < 50.0 or > 500.0 SIS-020305 MW < 50.0 or > 500.0 SIS-020306 MW < 50.0 or > 500.0 SIS-020353 Paranitrophenyl_esters < 0 or > 0 SIS-020354 MW < 50.0 or > 500.0 SIS-020355 Paranitrophenyl_esters < 0 or > 0 SIS-020378 MW < 50.0 or > 500.0 SIS-020384 MW < 50.0 or > 500.0 SIS-020436 MW < 50.0 or > 500.0 SIS-020451 MW < 50.0 or > 500.0 SIS-020489 MW < 50.0 or > 500.0 SIS-020498 MW < 50.0 or > 500.0 SIS-020499 MW < 50.0 or > 500.0 SIS-020537 MW < 50.0 or > 500.0 SIS-020546 MW < 50.0 or > 500.0 SIS-020547 MW < 50.0 or > 500.0 SIS-020548 MW < 50.0 or > 500.0 SIS-020562 MW < 50.0 or > 500.0 SIS-020563 MW < 50.0 or > 500.0 SIS-020564 MW < 50.0 or > 500.0 SIS-020583 MW < 50.0 or > 500.0 SIS-020584 MW < 50.0 or > 500.0 SIS-020594 MW < 50.0 or > 500.0 SIS-020595 MW < 50.0 or > 500.0 SIS-020596 MW < 50.0 or > 500.0 SIS-020611 MW < 50.0 or > 500.0 SIS-020612 MW < 50.0 or > 500.0 SIS-020613 MW < 50.0 or > 500.0 SIS-020636 MW < 50.0 or > 500.0 SIS-020637 MW < 50.0 or > 500.0 SIS-020648 MW < 50.0 or > 500.0 SIS-020649 MW < 50.0 or > 500.0 SIS-020650 MW < 50.0 or > 500.0 SIS-020665 MW < 50.0 or > 500.0 SIS-020666 MW < 50.0 or > 500.0 SIS-020667 MW < 50.0 or > 500.0 SIS-020677 MW < 50.0 or > 500.0 SIS-020690 MW < 50.0 or > 500.0 SIS-020691 MW < 50.0 or > 500.0 SIS-020701 MW < 50.0 or > 500.0 SIS-020702 MW < 50.0 or > 500.0 SIS-020703 MW < 50.0 or > 500.0 SIS-020717 MW < 50.0 or > 500.0 SIS-020718 MW < 50.0 or > 500.0 SIS-020724 MW < 50.0 or > 500.0 SIS-020725 MW < 50.0 or > 500.0 SIS-020727 MW < 50.0 or > 500.0 SIS-020738 MW < 50.0 or > 500.0 SIS-020739 MW < 50.0 or > 500.0 SIS-020740 MW < 50.0 or > 500.0 SIS-020743 MW < 50.0 or > 500.0 SIS-020750 MW < 50.0 or > 500.0 SIS-020751 MW < 50.0 or > 500.0 SIS-020752 MW < 50.0 or > 500.0 SIS-020765 MW < 50.0 or > 500.0 SIS-020766 MW < 50.0 or > 500.0 SIS-020767 MW < 50.0 or > 500.0 SIS-020773 MW < 50.0 or > 500.0 SIS-020774 MW < 50.0 or > 500.0 SIS-020775 MW < 50.0 or > 500.0 SIS-020780 MW < 50.0 or > 500.0 SIS-020781 MW < 50.0 or > 500.0 SIS-020782 MW < 50.0 or > 500.0 SIS-020783 MW < 50.0 or > 500.0 SIS-020784 MW < 50.0 or > 500.0 SIS-020785 MW < 50.0 or > 500.0 SIS-020786 MW < 50.0 or > 500.0 SIS-020789 MW < 50.0 or > 500.0 SIS-020795 MW < 50.0 or > 500.0 SIS-020796 MW < 50.0 or > 500.0 SIS-020808 MW < 50.0 or > 500.0 SIS-020809 MW < 50.0 or > 500.0 SIS-020810 MW < 50.0 or > 500.0 SIS-020816 MW < 50.0 or > 500.0 SIS-020817 MW < 50.0 or > 500.0 SIS-020818 MW < 50.0 or > 500.0 SIS-020820 MW < 50.0 or > 500.0 SIS-020826 MW < 50.0 or > 500.0 SIS-020827 MW < 50.0 or > 500.0 SIS-020828 MW < 50.0 or > 500.0 SIS-020829 MW < 50.0 or > 500.0 SIS-020830 MW < 50.0 or > 500.0 SIS-020831 MW < 50.0 or > 500.0 SIS-020832 MW < 50.0 or > 500.0 SIS-020835 MW < 50.0 or > 500.0 SIS-020837 MW < 50.0 or > 500.0 SIS-020841 MW < 50.0 or > 500.0 SIS-020842 MW < 50.0 or > 500.0 SIS-020843 MW < 50.0 or > 500.0 SIS-020844 MW < 50.0 or > 500.0 SIS-020857 MW < 50.0 or > 500.0 SIS-020858 MW < 50.0 or > 500.0 SIS-020859 MW < 50.0 or > 500.0 SIS-020864 MW < 50.0 or > 500.0 SIS-020865 MW < 50.0 or > 500.0 SIS-020866 MW < 50.0 or > 500.0 SIS-020874 MW < 50.0 or > 500.0 SIS-020875 MW < 50.0 or > 500.0 SIS-020876 MW < 50.0 or > 500.0 SIS-020877 MW < 50.0 or > 500.0 SIS-020878 MW < 50.0 or > 500.0 SIS-020879 MW < 50.0 or > 500.0 SIS-020880 MW < 50.0 or > 500.0 SIS-020883 MW < 50.0 or > 500.0 SIS-020889 MW < 50.0 or > 500.0 SIS-020890 MW < 50.0 or > 500.0 SIS-020891 MW < 50.0 or > 500.0 SIS-020892 MW < 50.0 or > 500.0 SIS-020906 MW < 50.0 or > 500.0 SIS-020907 MW < 50.0 or > 500.0 SIS-020918 MW < 50.0 or > 500.0 SIS-020927 MW < 50.0 or > 500.0 SIS-020936 MW < 50.0 or > 500.0 SIS-020942 MW < 50.0 or > 500.0 SIS-020943 MW < 50.0 or > 500.0 SIS-020950 MW < 50.0 or > 500.0 SIS-020951 MW < 50.0 or > 500.0 SIS-020958 MW < 50.0 or > 500.0 SIS-020959 MW < 50.0 or > 500.0 SIS-020961 MW < 50.0 or > 500.0 SIS-020963 MW < 50.0 or > 500.0 SIS-020967 MW < 50.0 or > 500.0 SIS-020968 MW < 50.0 or > 500.0 SIS-020969 MW < 50.0 or > 500.0 SIS-020970 MW < 50.0 or > 500.0 SIS-020971 MW < 50.0 or > 500.0 SIS-020976 MW < 50.0 or > 500.0 SIS-020977 MW < 50.0 or > 500.0 SIS-020982 MW < 50.0 or > 500.0 SIS-020983 MW < 50.0 or > 500.0 SIS-020984 MW < 50.0 or > 500.0 SIS-020985 MW < 50.0 or > 500.0 SIS-020986 MW < 50.0 or > 500.0 SIS-020991 MW < 50.0 or > 500.0 SIS-020992 MW < 50.0 or > 500.0 SIS-020993 MW < 50.0 or > 500.0 SIS-020994 MW < 50.0 or > 500.0 SIS-020995 MW < 50.0 or > 500.0 SIS-021292 MW < 50.0 or > 500.0 SIS-021395 MW < 50.0 or > 500.0 SIS-0214 MW < 50.0 or > 500.0 SIS-021547 MW < 50.0 or > 500.0 SIS-021603 MW < 50.0 or > 500.0 SIS-021604 MW < 50.0 or > 500.0 SIS-0228 MW < 50.0 or > 500.0 SIS-0267 MW < 50.0 or > 500.0 SIS-0277 MW < 50.0 or > 500.0 SIS-0288 MW < 50.0 or > 500.0 SIS-0326 MW < 50.0 or > 500.0 SIS-0359 MW < 50.0 or > 500.0 SIS-0407 MW < 50.0 or > 500.0 SIS-0439 MW < 50.0 or > 500.0 SIS-0457 MW < 50.0 or > 500.0 SIS-0490 MW < 50.0 or > 500.0 SIS-0567 Paranitrophenyl_esters < 0 or > 0 SIS-0570 MW < 50.0 or > 500.0 SIS-0573 MW < 50.0 or > 500.0 SIS-0587 MW < 50.0 or > 500.0 SIS-0600 MW < 50.0 or > 500.0 SIS-0625 MW < 50.0 or > 500.0 SIS-0646 MW < 50.0 or > 500.0 SIS-0654 MW < 50.0 or > 500.0 SIS-0655 MW < 50.0 or > 500.0 SIS-0656 MW < 50.0 or > 500.0 SIS-0694 MW < 50.0 or > 500.0 SIS-0721 MW < 50.0 or > 500.0 SIS-0893 MW < 50.0 or > 500.0 SIS-0905 MW < 50.0 or > 500.0 SIS-0907 MW < 50.0 or > 500.0 SIS-0908 MW < 50.0 or > 500.0 SIS-0918 MW < 50.0 or > 500.0 SIS-0919 MW < 50.0 or > 500.0 SIS-0920 MW < 50.0 or > 500.0 SIS-0921 MW < 50.0 or > 500.0 SIS-0935 MW < 50.0 or > 500.0 SIS-0943 MW < 50.0 or > 500.0 SIS-0946 MW < 50.0 or > 500.0 SIS-0947 MW < 50.0 or > 500.0 SIS-0950 MW < 50.0 or > 500.0 SIS-0965 MW < 50.0 or > 500.0 SIS-0966 MW < 50.0 or > 500.0 SIS-0971 MW < 50.0 or > 500.0 SIS-0972 MW < 50.0 or > 500.0 SIS-1014 MW < 50.0 or > 500.0 SIS-1017 MW < 50.0 or > 500.0 SIS-1023 MW < 50.0 or > 500.0 SIS-1024 MW < 50.0 or > 500.0 SIS-1027 MW < 50.0 or > 500.0 SIS-1028 MW < 50.0 or > 500.0 SIS-1081 MW < 50.0 or > 500.0 SIS-1114 MW < 50.0 or > 500.0 SIS-1120 MW < 50.0 or > 500.0 SIS-1128 MW < 50.0 or > 500.0 SIS-1163 MW < 50.0 or > 500.0 SIS-1166 MW < 50.0 or > 500.0 SIS-1172 MW < 50.0 or > 500.0 SIS-1189 MW < 50.0 or > 500.0 SIS-1233 MW < 50.0 or > 500.0 SIS-1234 MW < 50.0 or > 500.0 SIS-1235 MW < 50.0 or > 500.0 SIS-1242 MW < 50.0 or > 500.0 SIS-1247 MW < 50.0 or > 500.0 SIS-1251 MW < 50.0 or > 500.0 SIS-1252 MW < 50.0 or > 500.0 SIS-1254 MW < 50.0 or > 500.0 SIS-1266 MW < 50.0 or > 500.0 SIS-1267 MW < 50.0 or > 500.0 SIS-1270 MW < 50.0 or > 500.0 SIS-1272 MW < 50.0 or > 500.0 SIS-1273 MW < 50.0 or > 500.0 SIS-1274 MW < 50.0 or > 500.0 SIS-1275 MW < 50.0 or > 500.0 SIS-1276 MW < 50.0 or > 500.0 SIS-1277 MW < 50.0 or > 500.0 SIS-1298 MW < 50.0 or > 500.0 SIS-1299 MW < 50.0 or > 500.0 SIS-1302 MW < 50.0 or > 500.0 SIS-1304 MW < 50.0 or > 500.0 SIS-1314 MW < 50.0 or > 500.0 SIS-1327 MW < 50.0 or > 500.0 SIS-1328 MW < 50.0 or > 500.0 SIS-1330 MW < 50.0 or > 500.0 SIS-1416 MW < 50.0 or > 500.0 SIS-1491 MW < 50.0 or > 500.0 SIS-1492 MW < 50.0 or > 500.0 SIS-1566 MW < 50.0 or > 500.0 SIS-1567 MW < 50.0 or > 500.0 SIS-1570 MW < 50.0 or > 500.0 SIS-1593 MW < 50.0 or > 500.0 SIS-1650 MW < 50.0 or > 500.0 SIS-1694 MW < 50.0 or > 500.0 SIS-1695 MW < 50.0 or > 500.0 SIS-1714 MW < 50.0 or > 500.0 SIS-1758 MW < 50.0 or > 500.0 SIS-1783 MW < 50.0 or > 500.0 SIS-1789 MW < 50.0 or > 500.0 SIS-1814 MW < 50.0 or > 500.0 SIS-1903 MW < 50.0 or > 500.0 SIS-1930 MW < 50.0 or > 500.0 SIS-1972 MW < 50.0 or > 500.0 SIS-1974 MW < 50.0 or > 500.0 SIS-1977 MW < 50.0 or > 500.0 SIS-1982 MW < 50.0 or > 500.0 SIS-1983 MW < 50.0 or > 500.0 SIS-1988 MW < 50.0 or > 500.0 SIS-1989 MW < 50.0 or > 500.0 SIS-1990 MW < 50.0 or > 500.0 SIS-1991 MW < 50.0 or > 500.0 SIS-1993 MW < 50.0 or > 500.0 SIS-1994 MW < 50.0 or > 500.0 SIS-1996 MW < 50.0 or > 500.0 SIS-1997 MW < 50.0 or > 500.0 SIS-2007 MW < 50.0 or > 500.0 SIS-2015 MW < 50.0 or > 500.0 SIS-2018 MW < 50.0 or > 500.0 SIS-2019 MW < 50.0 or > 500.0 SIS-2022 MW < 50.0 or > 500.0 SIS-2024 MW < 50.0 or > 500.0 SIS-2034 MW < 50.0 or > 500.0 SIS-2035 MW < 50.0 or > 500.0 SIS-2037 MW < 50.0 or > 500.0 SIS-2051 MW < 50.0 or > 500.0 SIS-2055 MW < 50.0 or > 500.0 SIS-2063 MW < 50.0 or > 500.0 SIS-2074 MW < 50.0 or > 500.0 SIS-2086 MW < 50.0 or > 500.0 SIS-2091 MW < 50.0 or > 500.0 SIS-2092 MW < 50.0 or > 500.0 SIS-2251 MW < 50.0 or > 500.0 SIS-2255 Alkyl_halides < 0 or > 1 SIS-2256 Alkyl_halides < 0 or > 1 SIS-2257 Alkyl_halides < 0 or > 1 SIS-2258 Alkyl_halides < 0 or > 1 SIS-2259 Alkyl_halides < 0 or > 1 SIS-2260 Alkyl_halides < 0 or > 1 SIS-2261 Alkyl_halides < 0 or > 1 SIS-2262 Alkyl_halides < 0 or > 1 SIS-2263 Alkyl_halides < 0 or > 1 SIS-2306 Alkyl_halides < 0 or > 1 SIS-2307 Alkyl_halides < 0 or > 1 SIS-4894 Acid_halides < 0 or > 1 SIS-4897 MW < 50.0 or > 500.0 SIS-5059 MW < 50.0 or > 500.0 SIS-5060 MW < 50.0 or > 500.0 SIS-5061 MW < 50.0 or > 500.0 SIS-5062 MW < 50.0 or > 500.0 SIS-5063 MW < 50.0 or > 500.0 SIS-5254 MW < 50.0 or > 500.0 SIS-6136 MW < 50.0 or > 500.0 SIS-9252 MW < 50.0 or > 500.0 SIS-9312 MW < 50.0 or > 500.0 SIS-9317 MW < 50.0 or > 500.0 SPC-000054 MW < 50.0 or > 500.0 SPC-000056 MW < 50.0 or > 500.0 SPC-000057 MW < 50.0 or > 500.0 SPC-000060 MW < 50.0 or > 500.0 SPC-000077 MW < 50.0 or > 500.0 SPC-000080 MW < 50.0 or > 500.0 SPC-000100 MW < 50.0 or > 500.0 SPC-000101 MW < 50.0 or > 500.0 SPC-001885 MW < 50.0 or > 500.0 SPC-001943 MW < 50.0 or > 500.0 SPC-001945 MW < 50.0 or > 500.0 SPC-001946 MW < 50.0 or > 500.0 SPC-001982 MW < 50.0 or > 500.0 SPC-002001 MW < 50.0 or > 500.0 SPC-002005 MW < 50.0 or > 500.0 SPC-002006 MW < 50.0 or > 500.0 SPC-002022 MW < 50.0 or > 500.0 SPC-002049 MW < 50.0 or > 500.0 SPC-002064 MW < 50.0 or > 500.0 SPC-002079 MW < 50.0 or > 500.0 SPC-002082 MW < 50.0 or > 500.0 SPC-002096 MW < 50.0 or > 500.0 SPC-002097 MW < 50.0 or > 500.0 SPC-002244 MW < 50.0 or > 500.0 SPC-002260 MW < 50.0 or > 500.0 SPC-002262 MW < 50.0 or > 500.0 SPC-002264 MW < 50.0 or > 500.0 SPC-002277 MW < 50.0 or > 500.0 SPC-002279 MW < 50.0 or > 500.0 SPC-002284 MW < 50.0 or > 500.0 SPC-002285 MW < 50.0 or > 500.0 SPC-002303 MW < 50.0 or > 500.0 SPC-002343 MW < 50.0 or > 500.0 SPC-002365 MW < 50.0 or > 500.0 SPC-002366 MW < 50.0 or > 500.0 SPC-002384 MW < 50.0 or > 500.0 SPC-002644 MW < 50.0 or > 500.0 SPC-002685 MW < 50.0 or > 500.0 SPC-002707 MW < 50.0 or > 500.0 SPC-002725 MW < 50.0 or > 500.0 SPC-002783 MW < 50.0 or > 500.0 SPC-002804 MW < 50.0 or > 500.0 SPC-002817 MW < 50.0 or > 500.0 SPC-002845 MW < 50.0 or > 500.0 SPC-002846 MW < 50.0 or > 500.0 SPC-002878 MW < 50.0 or > 500.0 SPC-002963 MW < 50.0 or > 500.0 SPC-002965 MW < 50.0 or > 500.0 SPC-002966 MW < 50.0 or > 500.0 SPC-003145 MW < 50.0 or > 500.0 SPC-003146 MW < 50.0 or > 500.0 SPC-003184 MW < 50.0 or > 500.0 SPC-003218 MW < 50.0 or > 500.0 SPC-003222 MW < 50.0 or > 500.0 SPC-003224 MW < 50.0 or > 500.0 SPC-003237 MW < 50.0 or > 500.0 SPC-003263 MW < 50.0 or > 500.0 SPC-003266 MW < 50.0 or > 500.0 SPC-003296 MW < 50.0 or > 500.0 SPC-003297 MW < 50.0 or > 500.0 SPC-003298 MW < 50.0 or > 500.0 SPC-003308 MW < 50.0 or > 500.0 SPC-003310 MW < 50.0 or > 500.0 SPC-003314 MW < 50.0 or > 500.0 SPC-003326 MW < 50.0 or > 500.0 SPC-003334 MW < 50.0 or > 500.0 SPC-003385 MW < 50.0 or > 500.0 SPC-003482 MW < 50.0 or > 500.0 SPC-003502 MW < 50.0 or > 500.0 SPC-003505 MW < 50.0 or > 500.0 SPC-003506 MW < 50.0 or > 500.0 SPC-003531 MW < 50.0 or > 500.0 SPC-003566 MW < 50.0 or > 500.0 SPC-003567 MW < 50.0 or > 500.0 SPC-003584 MW < 50.0 or > 500.0 SPC-003627 MW < 50.0 or > 500.0 SPC-003660 MW < 50.0 or > 500.0 SPC-003686 MW < 50.0 or > 500.0 SPC-003964 MW < 50.0 or > 500.0 SPC-004058 MW < 50.0 or > 500.0 SPC-004059 MW < 50.0 or > 500.0 SPC-004060 MW < 50.0 or > 500.0 SPC-004061 MW < 50.0 or > 500.0 SPC-004062 MW < 50.0 or > 500.0 SPC-004083 MW < 50.0 or > 500.0 SPC-004086 MW < 50.0 or > 500.0 SPC-004118 MW < 50.0 or > 500.0 SPC-004122 MW < 50.0 or > 500.0 SPC-004123 MW < 50.0 or > 500.0 SPC-004136 MW < 50.0 or > 500.0 SPC-004137 MW < 50.0 or > 500.0 SPC-004146 MW < 50.0 or > 500.0 SPC-004148 MW < 50.0 or > 500.0 SPC-004149 MW < 50.0 or > 500.0 SPC-005168 MW < 50.0 or > 500.0 SPC-005233 MW < 50.0 or > 500.0 SPC-005262 MW < 50.0 or > 500.0 SPC-005573 MW < 50.0 or > 500.0 SPC-005630 MW < 50.0 or > 500.0 SPC-005648 MW < 50.0 or > 500.0 SPC-005670 MW < 50.0 or > 500.0 SPC-005853 MW < 50.0 or > 500.0 SPC-005872 MW < 50.0 or > 500.0 SPC-005924 MW < 50.0 or > 500.0 SPC-005935 MW < 50.0 or > 500.0 SPC-005977 MW < 50.0 or > 500.0 SPC-005995 MW < 50.0 or > 500.0 SPC-006023 MW < 50.0 or > 500.0 SPC-006058 MW < 50.0 or > 500.0 SPC-006163 MW < 50.0 or > 500.0 SPC-006245 MW < 50.0 or > 500.0 SPC-006650 MW < 50.0 or > 500.0 SPC-006670 MW < 50.0 or > 500.0 SPC-006724 MW < 50.0 or > 500.0 SPC-006748 MW < 50.0 or > 500.0 SPC-006750 MW < 50.0 or > 500.0 SPC-006773 MW < 50.0 or > 500.0 SPC-006789 MW < 50.0 or > 500.0 SPC-006798 MW < 50.0 or > 500.0 SPC-006807 MW < 50.0 or > 500.0 SPC-006909 MW < 50.0 or > 500.0 SPC-006967 MW < 50.0 or > 500.0 SPC-007032 MW < 50.0 or > 500.0 SPC-007087 MW < 50.0 or > 500.0 SPC-007089 MW < 50.0 or > 500.0 SPC-007107 MW < 50.0 or > 500.0 SPC-007133 MW < 50.0 or > 500.0 SPC-007147 MW < 50.0 or > 500.0 SPC-007158 MW < 50.0 or > 500.0 SPC-007169 MW < 50.0 or > 500.0 SPC-007182 MW < 50.0 or > 500.0 SPC-007187 MW < 50.0 or > 500.0 SPC-007193 MW < 50.0 or > 500.0 SPC-007207 MW < 50.0 or > 500.0 SPC-007388 MW < 50.0 or > 500.0 SPC-007392 MW < 50.0 or > 500.0 SPC-007469 MW < 50.0 or > 500.0 SPC-007570 MW < 50.0 or > 500.0 SPC-007574 MW < 50.0 or > 500.0 SPC-007593 MW < 50.0 or > 500.0 SPC-009430 MW < 50.0 or > 500.0 SPC-010059 MW < 50.0 or > 500.0 SPC-012563 MW < 50.0 or > 500.0 SPC-012567 MW < 50.0 or > 500.0 SPC-013124 MW < 50.0 or > 500.0 SPC-013484 MW < 50.0 or > 500.0 SPC-013499 MW < 50.0 or > 500.0 SPC-013568 MW < 50.0 or > 500.0